These 10 Clinical-Strength Deodorants Will Keep You Smelling Good All Summer Long
To help you find the best clinical-strength deodorant, we spoke to board-certified dermatologists and researched and personally tested dozens of products to find our top 10 based on effectiveness and ingredients.
Our Top Picks for the Best Clinical-Strength Deodorants
- Best for Women: Clinique Antiperspirant-Deodorant Roll-On
- Best for Men: Jack Black Pit Boss Antiperspirant & Deodorant
- Best Budget-Friendly: Secret Clinical
- Best for Working Out: Carpe Antiperspirant Underarm Lotion
- Best Moisturizing: Dove Clinical Protection
- Best Whole-Body: Duradry Antiperspirant Wipes
- Best Spray: Unlimited by Degree
- Best Wipes: SweatBlock Antiperspirant Wipes
- Best Fragrance-Free: Vanicream Anti-perspirant/Deodorant
- Best Roll-On: Certain Dri Clinical Strength

Best for Women
Clinique Antiperspirant-Deodorant Roll-On
Pros
- Gentle on sensitive skin
- 18-percent aluminum chlorohydrate
- Goes on clear, dries quickly
- Doesn’t transfer onto clothing
- Fragrance-free
Cons
- Goes on wet
- Contains alcohol, which may be irritating to some
Key Specs
- Strength: 18-percent aluminum chlorohydrate
- Type: Roll-on
- Scented: No
This sleek bottle — which is slimmer than most products — is incredibly easy to use due to its size and shape. It’s a roll-on antiperspirant, so it will feel wet when you first apply it, but it dries in less than a minute. On top of that, it’s 100-percent clear, both in the container and after application. There’s absolutely zero residue on your skin or clothing. In fact, after letting it dry, I wouldn’t even know I was wearing it. Despite the fact that it’s fragrance-free, it kept me smelling good even when I did sweat. If you want something that absolutely will not leave any white marks or residue on your skin or clothes, this is the best option around.

Best for Men
Jack Black Pit Boss Antiperspirant & Deodorant
Pros
- Powerful all-day protection
- 20-percent aluminum zirconium tetrachlorohydrate
- Moisturizing
- Goes on smooth
- Non-irritating formula
Cons
- Priciest on our list
- Scent may be too strong for some
- No fragrance-free option available
Key Specs
- Type: Stick
- Strength: 20-percent aluminum zirconium tetrachlorohydrate
- Scented: Yes
It goes on smoothly and feels very moisturizing. Even though it’s white in the container, it applies almost entirely clear. It dried quickly without leaving any residue on my skin or clothing. Best of all, it smells amazing, with five gender-neutral scent options to choose from. I chose the original scent, which has an earthy, citrusy smell. It’s definitely a stronger fragrance than typical deodorants for women, but I didn’t find it overpowering. Of all the deodorants I tested, this is the one that worked the best. It kept me dry even after working up a sweat, and the scent lasted all day.

Best Budget-Friendly
Secret Clinical
Pros
- Most affordable on our list
- 20 percent aluminum zirconium tetrachlorohydrex gly
- Lasts all day
- Goes on smooth
Cons
- Slight residue transfer to clothing
- Contains fragrance, which can cause skin irritation for some
Key Specs
- Type: Stick
- Strength: 20-percent aluminum zirconium tetrachlorohydrex gly
- Scented: Yes, including fragrance-free
Clinical-strength antiperspirants contain higher amounts of active ingredients, which makes them more effective at controlling sweat. Unfortunately, this can also make them pricier. But Secret Clinical offers incredible sweat protection at an affordable cost.
It contains 20-percent aluminum zirconium tetrachlorohydrex gly in a traditional deodorant stick. The texture is smooth and powdery, and while it’s not overly moisturizing, it’s also not drying or irritating. It comes in eight scents, such as Lavender, Shower Fresh, Coconut, and Free & Sensitive. It’s marketed as an invisible solid, and although it goes on clear for the most part, there can be some slight residue transfer to your clothes, which isn’t unusual for most deodorant sticks.

Best for Working Out
Carpe Antiperspirant Underarm Lotion
Pros
- Long-lasting, highly effective for tough workouts
- Contains 15-percent aluminum sesquichlorohydrate
- Includes glycerin and eucalyptus oil to moisturize
- Fragrance-free option available
Cons
- Longer drying time
- Texture is more like a lotion
Key Specs
- Strength: 15-percent aluminum sesquichlorohydrate
- Type: Stick
- Scented: Yes, including fragrance-free
Unlike most typical deodorant sticks, Carpe feels more like a lotion when you apply it, says Raki Swanson, a Minnesota-based writer who tested Carpe for Everyday Health. Because of that, it takes a bit more time to dry and fully sink into your skin. “Once it’s absorbed, there’s no indication you’re wearing it,” she says.
As for the efficacy, Swanson has high praise. “This is an utterly amazing product. I did not have a lot of sweat; I was bone-dry the entire time I used it,” she says. In fact, it worked so well that after the testing period she gave it to her teenage son, who works outside on a daily basis. “I had him use it, and he noticed that he didn’t sweat and he didn't smell. The anti-odor benefit is huge.”
It comes in a variety of scent options, too, including more masculine scents like Sandalwood and Mountain Breeze as well as traditionally feminine scents like Rose Water and Lavender Citrus. Swanson opted for Fresh Powder, which has a very clean, subtle fragrance. It’s not overwhelming, she says, and it’s perfect for both men and women.

Best Moisturizing
Dove Clinical Protection
Pros
- Includes sunflower oil, dimethicone, and other moisturizers
- 20 percent aluminum zirconium tetrachlorohydrex gly
- Helps reduce irritation from shaving
- Goes on dry and smooth
- Alcohol-free
Cons
- May leave some white residue
- No unscented option
Key Specs
- Strength: 20-percent aluminum zirconium tetrachlorohydrex gly
- Type: Cream
- Scented: Yes, no unscented option
This antiperspirant deodorant is made with Dove’s signature ¼ moisturizing cream, meaning that a quarter of the formula consists of moisturizing ingredients like sunflower oil and dimethicone. That’s especially helpful for anyone who suffers from underarm irritation after shaving.
Dove Clinical Protection is also alcohol-free, which means it’s less likely to cause skin irritation. The 20-percent aluminum zirconium tetrachlorohydrex gly works to prevent sweat, while the subtle, clean scent works to ensure you smell your best. But the gentle formula makes it ideal for those with sensitive skin, and it’s really beneficial for those with dry skin. During my testing, I noticed that it goes on dry and smooth and feels incredibly hydrating. It also didn’t leave any residue on my skin or clothes and didn’t clump up during the day.
However, it didn’t keep me quite as dry as the other products I tested. Part of that, though, comes from the container itself. It has a twist-up mechanism, so instead of a flat stick, the cream rolls out of small holes in the top of the container. Because of that, less product is dispensed with each use.

Best Whole-Body
Duradry Antiperspirant Wipes
Pros
- Convenient and easy to use
- 20-percent aluminum chlorohydrate
- Can be used anywhere you sweat
- Fragrance-free
Cons
- Can be drying
- Single-use wipes aren’t environmentally friendly
Key Specs
- Strength: 20-percent aluminum chlorohydrate
- Type: Wipes
- Scented: No
For people with hyperhidrosis, just using antiperspirant under their arms might not cut it. If you sweat a lot all over, you may want to consider a whole-body deodorant. Unfortunately, most whole-body deodorants are aluminum-free, meaning they won’t prevent sweating, only eliminate odor. That’s why Duradry Antiperspirant Wipes are such a game changer.
These wipes contain 20-percent aluminum chlorohydrate, so they block sweat to keep you dry everywhere. Aside from your underarms, you can use these wipes on your hands, feet, back, chest, groin, thighs, and any other body part that’s prone to sweating. The fact that they come in a wipe format makes them even better. Many whole-body deodorants come in creams or lotions, which can make application messy and awkward. Deodorant wipes, on the other hand, are a breeze. They’re premoistened with the right amount of antiperspirant, making them convenient to use. Unlike creamy formulas, they also dry faster, so you can use them on the go.

Best Spray
Unlimited by Degree
Pros
- Dries quickly
- 18-percent aluminum sesquichlorohydrate
- Doesn’t leave white residue
- Long-lasting sweat protection
- Four gender-neutral scent options
Cons
- No fragrance-free option
- Requires a well-ventilated area for application
Key Specs
- Strength: 18-percent aluminum sesquichlorohydrate
- Type: Spray
- Scented: Yes
If you prefer an antiperspirant deodorant spray, Unlimited by Degree is a good place to start. There are several benefits to using a spray deodorant instead of a stick. They dry quickly, leave less residue, and can offer a cooling sensation upon application, which is particularly nice during the hot summer months.
This dry spray contains 18-percent aluminum sesquichlorohydrate and features the brand’s exclusive SmartAdapt Tech, which works to adapt and respond to your body to create a barrier against sweat and odor. Basically, this microscopic barrier is activated in response to movement, heat, and stress. The spray goes on clear and dries within seconds, and the fragrance works for both men and women. There are four different gender-neutral scents to choose from: Bold, a fruity mango-and-jasmine fragrance; Clean, which is sweet and airy with notes of bergamot; Fresh, a crisp eucalyptus-and-mint scent; and Marine, which evokes a cool ocean aroma.

Best Wipes
SweatBlock Antiperspirant Wipes
Pros
- One wipe can last up to 7 days
- 15-percent aluminum chloride
- Convenient, individually wrapped wipes
- Fragrance-free
Cons
- Can be irritating for sensitive skin
- Single-use wipes aren’t environmentally friendly
Key Specs
- Strength: 15-percent aluminum chloride
- Type: Wipes
- Scented: No
If you’re looking for some seriously strong protection, SweatBlock is your best bet. These clinically strong antiperspirant wipes were created by a doctor to stop excessive sweating for a long time — seven days long.
The best way to use these is at night, right before going to bed. Apply to clean, dry skin and let air-dry for five minutes. In the morning, use your favorite deodorant for scent, with no need to worry about sweating. Since they come individually wrapped, they’re also easy to toss in your bag in case you forget to put on your deodorant before going out. However, they aren’t cheap. A pack of 10 individually wrapped wipes is around $20. But because each wipe is designed to last up to a week, that’s $20 for more than two months of protection.

Best Fragrance-Free
Vanicream Anti-perspirant/Deodorant
Pros
- Unscented
- Goes on dry
- Long-lasting protection
- Safe for sensitive skin
Cons
- Leaves some residue
- Slightly clumpy and thick
Key Specs
- Type: Stick
- Strength: 20-percent aluminum zirconium trichlorohydrex gly
- Scented: No
Heavily fragranced antiperspirants can seem like they work better, in part because the strong scent can mask any potential body odor. But if you have extremely sensitive skin, get headaches triggered by fragrance, or simply prefer being scent-free, this antiperspirant is the best option for you.
It has 20-percent aluminum zirconium trichlorohydrex gly, so it’ll keep you completely dry all day. It’s also free from parabens, dyes, alcohol, talc, preservatives, and, most importantly, any fragrance whatsoever. During my testing, that lack of fragrance really stood out. Often, even unscented products have a slight, subtle smell. Vanicream, on the other hand, literally has no smell. It comes in a typical stick format, but unlike other stick deodorants, it doesn’t really have a powdery feel. Instead, it has a smooth, thicker texture that’s almost like a lotion.
That thickness can be somewhat of a downside, though. I found that it would easily pill or clump up, even if I only used a small amount. Of all the products I tested, this one left the most residue. Again, because of how thick it was, it would clump almost immediately. However, it didn’t rub off on my clothing at all, and it kept me dry the entire day.

Best Roll-On
Certain Dri Clinical Strength
Pros
- Goes on clear
- No residue or clothing transfer
- Fragrance-free
- Highly effective
Cons
- Takes longer to dry
- May cause some skin irritation
Key Specs
- Strength: 15-percent aluminum chloride
- Type: Roll-on
- Scented: No
Comparison Table
How We Chose the Best Clinical-Strength Deodorants
To find the best clinical-strength deodorants, we researched dozens of top products, particularly those marketed to people with hyperhidrosis. We also consulted with several board-certified dermatologists to determine what to look for in a clinical-strength deodorant:
- Jill Waibel, MD, board-certified dermatologist in Miami
- Brendan Camp, MD, board-certified dermatologist in New York City
- Carolyn Jacob, MD, board-certified dermatologist in Chicago
All of the dermatologists agreed that the ingredient list is the most important thing to consider. With that in mind, we looked at the type and percentage of aluminum salt used as well as the inactive ingredients. After all the research, we narrowed down our list and put the products to the test. During testing, we paid particular attention to the following factors:
- Type of container and ease of use
- Product format and texture
- How it feels upon application
- Drying time
- Whether it left a residue on the skin or clothing
- Efficacy controlling odor and wetness
What to Look For in a Clinical-Strength Deodorant
The most important thing to look at when it comes to an antiperspirant deodorant is the ingredient list. Ingredients fall into two primary categories, both of which are worth paying attention to:
Active Ingredients Unlike deodorants, antiperspirants contain active ingredients — notably aluminum salts — in order to prevent sweat. There are several different types of aluminum salts, including aluminum chloride, aluminum chlorohydrate, aluminum zirconium, and aluminum sesquichlorohydrate.
Inactive Ingredients Aside from aluminum, antiperspirants will contain a multitude of other inactive ingredients that can help reduce odor or soothe skin. “For people with sensitive skin, look for products that offer more than odor protection, such as moisturizing ingredients, calming botanicals, and antioxidants that promote skin health,” says Dr. Camp. On the other hand, people with sensitive, dry, or eczema-prone skin should avoid antiperspirants with dyes or fragrances.
Application Type Antiperspirants come in a variety of formats, including solid sticks, roll-ons, creams, sprays, and wipes. The best one for you will depend on your personal preference, although your skin type may also play a role. “Creams are a good option for those with dry or sensitive skin,” Dr. Camp says. Wipes and sprays may be better for those desiring more convenience.
Texture While texture can depend on application type, different products may feel different on your skin. Some antiperspirant sticks have a gel-like texture, whereas others may feel thicker, smoother, or drier, almost like a powdery feeling.
Scent If you have sensitive skin, you’ll probably want to choose a fragrance-free antiperspirant. But if you want something that both blocks bad odor and makes you smell good, you may want to choose a scented product.
What’s the Difference Between Clinical-Strength and Regular Antiperspirant?
The term “clinical strength” is primarily a marketing tool, but it’s not a meaningless one, says Dr. Jacob. “It’s used to describe higher levels of aluminum, which can stop or decrease perspiration,” she explains. Regular antiperspirants contain between 10- and 15-percent aluminum, whereas clinical-strength products can contain as much as 20 percent.
While you may see the term “clinical-strength deodorant” used on packaging, that’s technically not accurate. Deodorant-only products don’t contain active ingredients like aluminum salts, so they work to control odor, not block sweat. Antiperspirant deodorants, on the other hand, aim to reduce sweat and odor.
What Is Hyperhidrosis, and What Causes It?
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Why Trust Everyday Health

Katie Mannion
Author
Katie Mannion is a St. Louis–based writer and occupational therapy assistant with clinical experience across multiple healthcare and education settings.
As a writer, Katie covers an array of topics, but is particularly focused on health, mental well-being, and skincare. Her work has been featured in publications such as People, SheKnows, and Yahoo, among other outlets.
In her free time, she enjoys kickboxing, watching reality TV shows, and spending time with her son.

Susan Bard, MD
Medical Reviewer
Susan Bard, MD, is a clinical instructor in the department of dermatology at Weill Cornell Medicine and an adjunct clinical instructor in the department of dermatology at Mount Sinai in New York City. Her professional interests include Mohs micrographic surgery, cosmetic and laser procedures, and immunodermatology.
She is a procedural dermatologist with the American Board of Dermatology and a fellow of the American College of Mohs Surgery.
Dr. Bard has written numerous book chapters and articles for many prominent peer-reviewed journals, and authored the textbook The Laser Treatment of Vascular Lesions.

Daniel Oakley
Fact-Checker
Daniel Oakley is a journalist, editor, and fact-checker. He has written, edited, taught, and produced media for Dow Jones, S&P Global, IHS Markit, Third Coast Studios Magazine, and 826 National.
Oakley's path has always been a health-and-wellness-focused one. A competitive triathlete and racing fundraiser for the Leukemia and Lymphoma Society, he also spends summer weekends as an ISA-certified surf instructor and Red Cross professional water rescuer with Laru Beya Collective in Rockaway Beach, which helps kids master and delight in their own backyard — the ocean. It has taught Oakley that “optimizing body and mind” flourishes precisely at the wellspring of community.

Lili Ladaga
Editor
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